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MAFLD is defined as hepatic steatosis with metabolic dysregulation, type 2 diabetes mellitus, overweight or obesity, and is characterized by extensive liver lesions, which can progress from isolated steatosis to metabolic dysfunction-associated steatohepatitis (MASH), liver fibrosis, and even HCC

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This may show that smaller spherical particles with higher density offer a more accessible interactive surface with less steric hindrance for aptamer coupling

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Data availability The data presented in this article may be provided by the corresponding author on reasonable request