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The highest levels of COX-2 are found mainly in suprabasal keratinocytes [103, 107]

Maintenance of glutamine anaplerosis and catabolism in cancer cells via increased GPT2 activity is essential for oncogenic KRAS -induced anchorage independent growth, as demonstrated by knockdown of GPT2 expression in HCT116 colon cancer cells [35]

A: Acetylcysteine Injection is to be administered intravenously (IV), meaning it is injected directly into a vein by a qualified healthcare professional

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