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Treatment with cisplatin only decreased cell viability to 40%

Importantly, ROS restriction and reduced cell mortality occur at lower Pinealon concentrations, while cell cycle modulation continues at higher concentrations, demonstrating that the peptide interacts directly with cellular genomic machinery beyond its antioxidant properties

Early genetically engineered NF1 heterozygous mouse models failed to recapitulate the characteristic symptoms of NF1 [50]

Finally, the sections were counterstained with hematoxylin for 20 seconds and dehydrated

Nile grass rats ( Arvicanthis niloticus ), a diurnal rodent, exposed to short photoperiod (5 h light/19 h dark) for 6 weeks presented reduced saccharin preference, higher immobility time in the forced swim test, and no changes on time spent in the light side of the dark/light box in comparison to controls (Figure 1), rats develop into depressive-like phenotypes (i.e., anhedonia, sexual dysfunction, increased immobility in the forced swim test) ( Landgraf et al

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