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McShane PJ, Naureckas ET, Tino G, Strek ME

Consider Timing and Dosage Why : The timing of supplements can affect their absorption and efficacy

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Since peristaltic activity is regulated by the enteric nervous system (ENS), we evaluated the number of differentiated enteric neurons and neuronal precursors (labelled with HuC/D and Sox10, respectively), but found no differences between treated and control larvae (Additional file 3: Figure 2 C), suggesting that BSSG may affect the functionality of enteric innervation rather than its density
Immunomodulatory treatments that affect disease progression and activity have not been identified for pSS and remain unmet clinical needs

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