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[DOI] [PMC free article] [PubMed] [Google Scholar] [90].Margolis DA, Gonzalez-Garcia J, Stellbrink H-J, Eron JJ, Yazdanpanah Y, Podzamczer D, Lutz T, Angel JB, Richmond GJ, Clotet B, Gutierrez F, Sloan L, Clair MS, Murray M, Ford SL, Mrus J, Patel P, Crauwels H, Griffith SK, Sutton KC, Dorey D, Smith KY, Williams PE, Spreen WR, Long-acting intramuscular cabotegravir and rilpivirine in adults with HIV-1 infection (LATTE-2): 96-week results of a randomised, open-label, phase 2b, non-inferiority trial, Lancet

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HD has been hypothesized to be caused by an abnormal expansion of the polyglutamine repeat at the N-terminus of the mutant Huntingtin (HTT) protein, leading to brain atrophy primarily within the striatum and cerebral cortex