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Besides, the ablation of the cox10 gene in PV interneurons of mice resulted in progressive loss of cytochrome oxidase, which is a terminal enzyme of the electron transfer chain, and was accompanied by an excitation/inhibition imbalance, as well as behavioral alterations similar to schizophrenia [211]

An important signature of regenerative drugs is the ability to produce such phenotypic cellular changes

Moir S, Ho J, Malaspina A, Wang W, DiPoto AC, OShea MA, et al

A dose threshold for a medium transfer bystander effect for a human skin cell line
