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At the mechanistic level, NCs modulate several signaling pathways, such as PI3K/AKT/mTOR, NF-B, MAPK, and Wnt/-catenin pathways

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CSF1R ligands IL-34 and CSF1 are differentially required for microglia development and maintenance in white and gray matter brain regions

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[DOI] [PubMed] [Google Scholar] 35.Pinkus R, Weiner LM, Daniel V