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Patients with severe influenza A virus infection (H1N1, H5N1, and H7N9) were found to have high levels of circulating pro-inflammatory cytokines [58]

Mansouri et al

Vitamin D has been shown to reduce serum levels of inflammatory cytokines, including IL-3 (151), IL-17 (151, 152), IL-1, IL-6, IL-8, and TNF- (153), and may directly act on CD4 + T cells to promote the secretion of the anti-inflammatory cytokine IL-10 by T regulatory cells (Tregs), controlling the further expansion of the inflammatory response (151, 152, 154, 155)