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Unlike vitamins, LC is synthesized endogenously in humans but becomes conditionally essential under certain physiological demands, such as prolonged or high-intensity exercise (Alesci et al

Melatonin supplements can help improve sleep quality

[DOI] [PMC free article] [PubMed] [Google Scholar] 187.Ng DP, Salim A, Liu Y, Zou L, Xu FG, Huang S, Leong H, Ong CN

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The timeline of Strongest Citation Bursts reveals evolving trends within the field

However, these combination effects are highly dependent on experimental models and co-administered components: synergistic metabolic improvements have been observed in animal studies (80), whereas some human studies report only modest reductions in liver enzymes without significant changes in broader metabolic parameters (64)