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Mitochondrial state 3 to 4 respiration transition during Fas-mediated apoptosis controls cellular redox balance and rate of cell death

[DOI] [PMC free article] [PubMed] [Google Scholar] 176.Shoda J., Kano M., Oda K., Kamiya J., Nimura Y., Suzuki H., Sugiyama Y., Miyazaki H., Todoroki T., Stengelin S., et al

Smad family proteins are downstream of the TGF- signaling pathway, and include receptor-regulated Smads, common pathway Smads, and inhibitory Smads

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In 2023, Lopez-Otin proposed twelve markers of aging, including genomic instability, telomere loss, epigenetic changes, loss of protein balance, failure of macroautophagy, dysregulated nutrient sensing, mitochondrial dysfunction, cell senescence, stem cell depletion, altered intercellular communication, chronic inflammation, and dysbiosis

Reported values for GSH and GSSG in human blood from healthy people
