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There are also serious ethical and legal concerns, as nootropics could become a public health issue
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Further, NLRP3 activation, which we and others have shown to be affected by dopamine, is implicated in depressive behaviors, and can be modulated by current antidepressant therapies (Alcocer-Gomez et al., 2014, 2017
doi: 10.4049/jimmunol.178.3.1809
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