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A central role for the polyamines in the aetiology of schizophrenia

If normal, start 1000 mcg oral b12 daily as prevention given multiple risk factors (age, metformin, PPI, now semaglutide)

Cell Mol Life Sci 70:17531761 Halliday MR, Pomara N, Sagare AP, Mack WJ, Frangione B, Zlokovic BV (2013) Relationship between cyclophilin A levels and matrix metalloproteinase 9 activity in cerebrospinal fluid of cognitively normal apolipoprotein E4 carriers and blood-brain barrier breakdown

Part A 17 , 161169 (2011)

An increasing understanding of the mechanisms underlying nociceptive signaling has positioned analgesic peptides as promising alternatives to conventional opioid drugs for the treatment of chronic and neuropathic pain, without the risk of tolerance or addiction

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