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Why does vitamin B12 deficiency take years to develop if it's water soluble

Recently, Ramana et al

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Cell Mol Immunol 21 , 103118 (2024)

Polygonum Multiflorums Natural Power : From South Korea, a 2020 study (still influencing 2025 research) in BMC Complementary Medicine and Therapies showed Polygonum multiflorum extract elongates anagen in human dermal papilla cells by upping anti-apoptotic Bcl2 and slashing catagen-trigger Dkk-1

It is produced naturally in the liver and plays a crucial role in neutralizing free radicals, detoxifying the body, and supporting the immune system