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This cascade of oxidative stress can lead to cellular dysfunction and damage, significantly impacting various tissues and organs [174, 175]

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Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1

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doi: 10.1097/MD.0000000000034758, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 124

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Each group included 15 patients and only patients in group one (arm I) received L-carnitine supplementation in addition to KDT

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