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Adhesion assay findings on the aorta of C57BL/6 mice reinforced the deduction that TMAO promotes the adhesion of monocytes to the aorta, with a maximum dose of TMAO at 10 mmol/L (51)

Lavaee, P., S

Specifically, parathyroid hormone 1 receptor (PTH1R) was deleted in Prx1 expressing SSCs to block the parathyroid hormone (PTH) signaling pathway, which led to low bone formation with increased bone resorption and high BMAT (152)

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Allosteric regulation of ARs transcriptional activity The mechanistic insights reported above are consistent with allosteric regulation of transcription factor action, in which the type of DNA motif to which the factor binds and its protein and ligand interactions influence its conformational plasticity and the availability of tunable multimerization and protein interaction surfaces that control context-dependent and gene-specific transcriptional activity [78, 80]

Sareen, D