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Epidemiol 8, 243 (2022)

Science 269 , 14021406 (1995)

Bloodbrain barrier disruption and neurovascular unit dysfunction in diabetic mice: protection with the mitochondrial carbonic anhydrase inhibitor topiramate

At a low dose (2.5 mg/kg), neuronal and glial cells in the cortical and hippocampal regions showed improved regularity, although some disorganization persisted

Additional proteins and lipids within ISGs (e.g., mannose-6-phosphate receptor, carboxypeptidase D, and Golgi-associated -ear-containing ARF-binding protein) are selectively removed via clathrin-coated vesicles and recycled back to the TGN via retrograde trafficking or to another compartment (e.g., endosomes) via anterograde trafficking

doi: 10.1089/ars.2010.3496