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The tumor cells that dwell in the origin sites secrete various cytokines floating or packed in vesicles such as in exosomes via bloodstream to activate the metastasis-prone niches, attracting rare tolerant subclones to distant colonization [147, 148]

doi: 10.1016/S0142-9612(03)00213-8 241

doi: 10.1038/srep33944

Then, the remained samples were centrifuged for 20 min at 12,000 G in 4C and the supernatant was separated for analysis of GST and GPx enzymatic activities, and GSH levels

These differences mean that impressive mouse results frequently translate to modest human outcomes

This generally is not critical in testing male Caucasians, but it certainly is a problem in diagnosing some Caucasian females and blacks of both sexes, especially during the reticulocytosis following acute hemolysis