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[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Paterson BM, Lammers KM, Arrieta MC, Fasano A, Meddings JB

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In the chronic inflammatory state, TNF- shifts the predominant cytokine environment towards pro-inflammatory cytokines, such as IL-1, IL-6, IL-17, IL-22, and interferon gamma (IFN-), while simultaneously reducing the secretion of anti-inflammatory cytokines, in particular IL-4 and IL-10 [12,13]

Material and methods Literature search To compile available in vitro and in vivo comet assay data on NAs we conducted a literature search focusing on primary publications