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doi: 10.1016/j.jconrel.2023.01.070

The strongest, proven benefits for skin come from topical application

Maximum results develop over six to twelve months of consistent use

The most recent clinical study assessing LDN in patients with inflammatory bowel disease involved 19 Ulcerative colitis patients and 28 patients affected by Crohns disease

Although it continues to attract interest in peptide medicine communities, the clinical research remains limited and somewhat controversial

Balanced MMP and TIMP expression supports tissue remodeling rather than fibrosis
