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Despite its relatively low expression in tumors, IL-4 signaling can have profound effects on TME programming, as even a small fraction of IL-4-producing cancer cells can drive significant immune suppression
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The A1 phenotype of astrocytes increases the expression of genes related to the complement cascade and neurotoxins, leading to a neurotoxic effect
In contrast to free -Syn monomers, the presence of -Syn oligomers within exosomes facilitates enhanced cellular absorption and more efficient dissemination (Valencia et al., 2022)
[DOI] [PubMed] [Google Scholar] 29.Tortolani D., Di Meo C., Standoli S., Ciaramellano F., Kadhim S., Hsu E., Rapino C., Maccarrone M
