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Examples of Bayesianbased study designs that incorporate both toxicity and efficacy include the EffTox design46 or TriCRM.47 It is also important to consider the PK/PD relationship in elucidating a biologically active dose range as supported by the task force on Methodology for the Development of Innovative Cancer Therapies.48 What else can be considered

Accordingly, results from the latter study, where blood was collected from 0 to 120 hours, are presented (Table 3)

[DOI] [PMC free article] [PubMed] [Google Scholar] Xiao W

Community oral protocols are typically once daily

BPC was first isolated form the human gastrointestinal tract where it is known to have anti-inflammatory and healing properties

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