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Also, the mapping approach for transcriptomic data is based on the inclusion of highly transcribed genes and therefore is biased towards more abundant proteins, hence potentially missing lowly abundant proteins relevant for viral replication

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Compared to empty vector controls, Rv0801 significantly suppressed Nrf2 mRNA expression ( Figure 5A ), accompanied by reduced transcription of antioxidant genes nqo1 , gclc , and txnrd1 ( Figure 5B )