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Snord3a transcriptionally activates STING signaling, and its targeted inhibition with antisense oligonucleotides demonstrates therapeutic efficacy in murine acute kidney injury models (118)
In addition to this pathway, newer work provides evidence of a novel Syk-independent means by which the BCR complex is sensed in the endoplasmic reticulum (ER) to then signal to mitochondria [75]
Crosstalk of Reactive Oxygen Species and NF-kappaB Signaling
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