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Some patients experience mild gastrointestinal symptoms, particularly with oral peptides, or transient fatigue during the adjustment period

Mol Cell Biol 40(13):e000990-20 Tonelli C, Chio IIC, Tuveson DA (2018) Transcriptional regulation by Nrf2

Rat Male SpragueDawley rats (68 weeks old, 200300 g

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Hypertens Res 47(4):859866

A targeting vector is electroporated into embryonic stem cells and this will insert the gene at a specific site within the genome using homology arms that flank the gene of interest