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Supplementary Materials Data Availability Statement Data is contained within the article.

Several probiotic strains have been shown to modulate Th17 cells and their related cytokines in lupus models through specific metabolites and signaling pathways metabolites and signaling pathways
Experimental studies indicate that supraphysiological testosterone exposure increases reactive oxygen species generation within cardiomyocytes while reducing the activity of endogenous antioxidant enzymes, including superoxide dismutase and glutathione peroxidase (72)

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10.1111/all.13948

Understanding why requires a closer look at how these molecules function inside the body