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Plasma zinc levels have been found to be significantly reduced in severe acne sufferers compared to those with mild-to-moderate acne in a study on 94 subjects (Ozuguz 2013)

After treatments, most of ACs recovered to the normal level, except for the hydroxyoctadecadienoylcarnitine (C18:2-OH), octadecadienylcarnitine (C18:2), eicosadienoylcarnitine (C20:2)

A trial comparing 45 women taking 150 mcg desogestrel + 30 mcg ethinyl estradiol to 46 women taking 150 mcg levonorgestrel + 30 mcg ethinyl estradiol (an older OCP) showed that the decrease in acne was significantly higher in the first group (Sanam 2011)

Accordingly, tissue damage of varying severity results in long recovery times after the acute phase of COVID-19 infection