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The key distinction: an NNMT inhibitor raises NAD+ indirectly, by protecting its raw material, rather than supplying it directly the way an NMN or NR supplement does
The area postrema downregulates amylin receptor density in response to sustained agonism, which is how nausea resolves over time
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10.1016/j.stem.2019.09.003 Cell Stem Cell 81 OConnellD
