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In the alignment of G6PD coding sequences from all organisms, those of Plasmodia stand out because they have a long 5 extension, which encodes the metabolically related enzyme 6-phosphoglucono--lactonase

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Moreover, western blot analysis showed that Hcy treatment (200 M, 96h) and/or MARS1 overexpression significantly enhanced HMGB1/2 K-Hcy levels in HCMECs, with no observed changes in acetylation (Figure 4H)

doi: 10.1016/j.kisu.2020.12.002 199 HatanakaTNaganumaAKakizakiS