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Obesity Excess body fat increases aromatase enzyme activity, which converts testosterone to estrogen

Given the limited sample size and absence of external validation, ROC findings should be interpreted as exploratory and indicative of potential candidate biomarkers rather than definitive diagnostic markers

We also acknowledge the Bill and Melinda Gates Foundation for availing the grants for the project

This dimerization of GPX4 and GSH is reversible by reduction

Similarly, histone 3 methylation at lysine residues 9 or 27 can downregulate EGFR expression levels, which is amplified in colorectal cancer (CRC) and linked with transcriptional repression [109]

10.1152/ajpendo.1997.272.2.E181 276 ShemyakinA.KovameesO.RafnssonA.BohmF.SvenarudP.SettergrenM.et al (2012)