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Finally, in an HD mouse model, the loss of HAP1 resulted in neuronal degeneration in the striatum [216]

In pathological muscle environments, such as Duchenne muscular dystrophy (DMD) and myocardial infarction, macrophages exhibit distinct pro-fibrotic phenotypes

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First-in-human study of ABBV-075 (mivebresib), a pan-inhibitor of bromodomain and extra terminal (BET) proteins, in patients (pts) with relapsed/refractory (RR) acute myeloid leukemia (AML): Preliminary data

CJC-1295 without DAC (Modified GRF 1-29): This version contains the same four protective amino acid substitutions but lacks the DAC linker