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It acts as a growth hormone (GH) secretagogue stimulating levels of GH and insulin-like growth factor 1 (IGF-1), while preserving GH pulsatility

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"Biochemical indicators of B vitamin status in the US population after folic acid fortification: results from the National Health and Nutrition Examination Survey 19992000"

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This observed relation between low vitamin B-12 concentrations in pregnancy and child insulin resistance was also supported by data from Nepal, but supplementation of pregnant women with vitamin B-12containing micronutrients was not found to affect child HOMA-IR (40)