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The mutation links to a decreased ability to detoxify
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10.1080/10717544.2017.1340362 93 HolmS.MaroudasA.UrbanJ

RT-qPCR of mouse dorsal skin after treatment further confirmed the upregulation of IGF-1, VEGF, Elastin, and HAS2, while the downregulation of TNF- and IL-1

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The role of cortistatin in the human immune system
