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Although ectopic attachment of refluxed menstrual debris remains a plausible mechanical explanation for endometriosis development, it cannot account for all incidences of disease occurrence given that the majority of cycling women exhibit this phenomenon, yet only a subset develop disease (Halme et al., 1984)

Shin Low et al., 2021
Oral administration of KPV will diminish the inflammatory responses of epithelial and immune cells in the colon

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These phase I quinone reactive metabolites, due to their capacity of forming covalent bonds with macromolecules containing nucleophiles groups or to their potential to induce redox cycling, were suggested to be implicated in liver injury
