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In hemodialysis patients, due to reduced renal clearance, carnitine depletion and acylcarnitine accumulation become significant, resulting in an abnormal increase in the ratio of acylcarnitine to free carnitine in plasma, which in turn inhibits cardiac fatty acid metabolism [261]

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Diaminobenzidine solution (K346811, DAKO, USA) was then added and incubated for 8 min, followed by counterstaining with Harris Hematoxylin, dehydration through graded ethanol to xylene, and coverslipped

A., and Pusey, C