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A human RCT from Wuhan, China, showed that ALA therapy (1200 mg/d) for 7 days, could reduce a 30-day all-cause mortality rate (37.5%) in critical COVID-19 patients 535
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These protective effects may be connected to the metabolic sponge function of transplanted mitochondria and the regulation of mitophagy
A further safety concern highlighted by the ADDF is the possibility that synthetic or isolated preparation of epithalon may constrain impurities and pose a safety risk [1]
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& Sung, G
