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The resulting reaction time and sample volume was divided by the NADH released to determine ALDH activity (mU/mL)

33 , 905922.e906 (2021)

Ethics declarations Ethics approval All of the experimental procedures were performed under the guidelines outlined by the National Research Councils Guide for the Care and Use of Laboratory Animals and were approved by the Atatrk University Local Ethics Council for Animal Experiments (protocol no.: 20213/63)

receives financial support from the Novo Nordisk Foundation (NNF23OC0081873) and the Swedish Brain Research Foundation (FO2023-0292)

1c, d) 42,58 , a rather unspecific GSH-dependent monothiol mechanism might be better suited for the reduction of a variety of physiological non-glutathione disulfide substrates to maintain metabolites and proteins in a reduced state (Fig

On a chemical level, the negative effects of oxidative stress can be traced to the impact of reactive oxygen species (ROS), a group of unstable, electron-rich molecules that drive the oxidation of diverse biomolecules