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5-amino-1MQ did not inhibit NAMPT up to a tested concentration of 100 M

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At the same time, the peptide inhibits lipogenic enzymes including acetyl-CoA carboxylase and fatty acid synthase, preventing the formation of new fat even when calories are in excess

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For example: FDA communications indicate AOD-9604 was removed from Category 2 in 2024 because nominations were withdrawn, while also noting FDA would consult the Pharmacy Compounding Advisory Committee (PCAC) about potential inclusion on the 503A bulks list