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In addition to antibody isotype, the location and geometry of the antibody-binding epitope, stoichiometry of the antibody to antigen and affinity of the antibody for both its antigen and its cognate FcR are all crucial determinants of immune effector cell activation 21,22

doi: 10.5603/NMR.2011.0006 4 LiscoGAccardoGPupilliCMalandrinoPDe GeronimoVTriggianiV

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