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coli , they each caused the aberrant accumulation of acylated glutathione thioesters, showing a surprising degree of enzyme-specific ligand selectivity in terms of chain length, oxygenation and desaturation ( Strep -binding motif, that allowed for the selective recovery of protein-ligand complexes using this tag (Figure 1)

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It is an important intracellular antioxidant

Bugdaci MS, Zuhur SS, Sokmen M, Toksoy B, Bayraktar B, Altuntas Y

The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop

Stabilization of wild-type p53 and induction of p21 can decrease the susceptibility of cancer cells to ferroptosis by conserving intracellular GSH (Tarangelo et al, 2018)