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Finally, in chromatin remodeling, complexes such as SWI/SNF regulate nucleosome positioning to influence DNA accessibility for transcription factor binding, and their dysfunction leads to chromatin structural abnormalities that promote thyroid carcinogenesis (Fig

Liver cytosolic antioxidants and related enzymes

Deficits in bioenergetics and impaired immune response in granulocytes from children with autism

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Ascorbate supplementation markedly improves the differentiation of midbrain derived neural stem cell against dopaminergic neurons, which is associated with the TET-mediated 5hmC generation and Jmjd3 catalyzed loss of H3K27m3 (He et al., 2015)

doi: 10.1007/s11434-016-1129-4