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Selective c-Met inhibitors have a very high selectivity (more than ten thousand times) for c-Met compared to other kinases [155]

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This gap results from interaction between residues close to the terminals and the charges of these terminals as a residue that is in the parent L-peptide close to the positively charged N-terminus will now be close to the negatively charged C-terminus, and vice versa

The FOXO4p53 axis in senescence p53 is a major tumour suppressor and master regulator of cellular stress responses: DNA damage, oxidative stress, oncogene activation