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Trx and GSH inhibition may lead to a reprogramming of the immune response, tilting the balance between the immune system and cancer or HIV in favor of the former, allowing elimination of diseased cells

Our standard process looks like this
An acquired deficiency in glutathione, as with alcohol or paracetamol, results in loss of this negative feedback and increased production of 5-oxoproline leading to a metabolic acidosis

According to the public registry, the trial was completed, and the results suggest a favorable safety profile with no significant adverse events reported (ClinicalTrials.gov Identifier: NCT03416053)
Investigation of optimal combination protocols represents another important research direction
