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Rare allergic reactions (particularly in individuals sensitive to sulfa, due to methionine)

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The compound's role in advancing our understanding of aging mechanisms, developing intervention strategies, and exploring the research potential of senescent cell elimination positions it at the forefront of aging research priorities

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Overcoming the drug resistance of MET-TKIs and ICIs, as well as their toxic and side effects that may affect the drug efficacy, remains a critical challenge

van Wijck K, van Eijk HMH, Buurman WA, Dejong CHC, Lenaerts K