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The therapeutic landscape has witnessed the emergence of various pharmacological strategies tailored to orchestrating cell death, with a particular focus on triggering ferroptosis by directing their efforts toward depleting GPX4

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3 / : (AGA)

Tirzepatide takes a fundamentally different approach

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Its not clear whether the same effect occurs in humans, and large reviews of human data from 2024 to 2025 have not shown an increased risk, but the family-history exclusion remains in place across all GLP-1 SmPCs