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This was observed in primary fibroblasts from FXTAS-affected subjects ranging from stages 2.5 to 5

[PubMed 4014252] 986

YoshimatsuHYonezawaAYamanishiKYaoYSuganoKNakagawaSet al

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doi: 10.24925/turjaf.v11is1.2505-2511.6413 50

This is a sophisticated statistical approach that goes beyond simply averaging results it analyses multiple variables simultaneously and isolates the independent effect of each treatment while controlling for factors that might distort the comparison