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MMA rises when there is not enough B12 in the mitochondria (the cells energy factories) to process fats and proteins so that they can be burnt as fuel for energy

This biochemical starvation directly contributes to the severe mood dysregulation, sleep disturbances, and the profound cognitive blankness often described by patients as brain fog

Warnings: Patients with early Leber's disease (hereditary optic nerve atrophy) may experience severe and rapid optic atrophy when treated with vitamin B12. Additionally, treating severe megaloblastic anemia with vitamin B12 can lead to fatal hypokalemia due to increased erythrocyte potassium requirements

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The best you can do is have an open conversation with your provider, considering the minimal potential risks against your own comfort and needs when discussing your medication options

As we grow older, cell renewal and repair slow down, which can be delayed by getting enough vitamins and nutrients, like vitamin B12