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Are we studying the right cell types

Microglia surrounding amyloid plaques in genetic mouse models of AD have been characterized by their altered transcriptional profile and have historically been referred to as disease associated microglia (DAMs), also known as activated response microglia (ARMs) 12,13

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Historically, the prognosis in neonates with hyperammonaemia was poor, but current treatments, along with prompt identification of hyperammonaemia, have considerably improved the survival of affected neonates 16 (Fig

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