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However, its important to note that individual results vary and more high-quality studies are needed

doi: 10.1111/nmo.13366 70 FagundesRRBeltSCBakkerBMDijkstraGHarmsenHJMFaberKN

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KhannaAKMeherSPrakashSTiwarySKSinghUSrivastavaAet al

Patients should be counseled never to administer extra doses to make up for missed doses, as this could increase the risk of adverse effects without providing additional therapeutic benefit

12 In addition, Asp can promote the activation of hypoxia-inducible factor HIF-1 and inflammasome in M1 macrophages and increase the production of Asn and other metabolites
