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Notably, KA administration resulted in a significant reduction in GSH, SOD, and CAT levels when compared to control and BA-treated mice

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Biochem Pharmacol 173:113820 Katsuoka F et al (2019) Direct and specific functional evaluation of the Nrf2 and MafG heterodimer by introducing a tethered dimer into small Maf-deficient cells

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This regulatory mechanism underscores DJ-1s crucial role in cellular defense against oxidative stress, highlighting its potential as a therapeutic target for neurodegenerative diseases and conditions involving oxidative damage (Ge et al., 2022

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A peptide is simply a chain of amino acids joined together

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In the nucleus, ACSS2 interacts with TFEB and facilitates site-specific H3K9 acetylation at the promoters of autophagy and lysosomal genes, including LAMP1, ATG5 , and GABARAPL1 , thus increasing transcription and promoting cell survival under stress

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Representatives of non-enzymatic antioxidants in higher plants are ascorbic acid (vitamin C), glutathione, flavonoids, isoprenoids, carotenoids, tocopherol (vitamin E), ubiquinone, and plastoquinone

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