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Autophagy as a potential therapeutic target in intervertebral disc degeneration
In addition, Sekhars work revealed that supplementing GlyNAC to older people and HIV-patients reversed other abnormalities including inflammation, endothelial dysfunction, insulin resistance, and improved muscle strength, exercise capacity, cognitive decline, gene-damage, and body composition
The PCR fragments 350 bp were purified using NUCLEOSPIN Gel and PCR Clean-up (MachereyNagel)
By keeping ROS in check, glutathione helps to maintain the delicate balance between oxidation and antioxidation, ensuring that our cells stay healthy and vibrant (Sies, 2015)
In addition, we used two AMPK agonists (AICAR and metformin) on H9C2 cells for verification
Cyclic guanosine monophosphate (cGMP)-a cyclic nucleotide has also been proposed as a second messenger pathway
